The CYP1A1 Antibody (C-term) from MyBioSource.com is a Mouse Monoclonal antibody to CYP1A, CYP1A1, P-450MC, and P1-450. This antibody recognizes Human antigen. The CYP1A1 Antibody (C-term) has been validated for the following applications: ELISA, and Western Blot.
Description
This gene, CYP1A1, encodes a member of the cytochrome P450
superfamily of enzymes. The cytochrome P450 proteins are
monooxygenases which catalyze many reactions involved in drug
metabolism and synthesis of cholesterol, steroids and other lipids.
This protein localizes to the endoplasmic reticulum and its
expression is induced by some polycyclic aromatic hydrocarbons
(PAHs), some of which are found in cigarette smoke. The enzyme's
endogenous substrate is unknown; however, it is able to metabolize
some PAHs to carcinogenic intermediates. The gene has been
associated with lung cancer risk. A related family member, CYP1A2,
is located approximately 25 kb away from CYP1A1 on chromosome 15